The Greeks lost either 1,500 or 2,000 men, which was a devastating setback.

Industry experts say the failure to set an achievable goal at the beginning and follow through has been a devastating setback.

Only three ships ever sailed again, a devastating setback to the French channel fleet.

But for Republicans this was not the devastating setback it appeared.

In Michaelmas term 1567/8, however, his fortunes received a devastating setback.

After the devastating setbacks of the last few days Li Yuan would never agree to blanket testing.

Today's Columns Young, male, blue-collar workers suffered devastating setbacks during the 1980's.

The office has also had devastating setbacks.

"Failure to pass the measure would be a devastating setback," he said.

That would be a devastating setback to American foreign policy, conjuring up images of American weakness.