Human activities can have a large and sometimes devastating impact on these factors.

This is having a devastating impact on the middle and working classes.

But for Martin, who was 22 at the time, the loss didn't have the same devastating impact.

And it will have a "devastating impact" on the poor.

This will have a devastating impact on small businesses and jobs.

These laws have had a devastating impact on the women in that state.

They can have a devastating and sometimes permanent impact on your health.

This has had a devastating impact in a lot of communities.

Remind us about the devastating impact of 9/11 on our country, and we all will.

He said the loss of more aid would have a "devastating impact."