The defense was fourth-best against the run (74.9 yards allowed per game).

How much will the secondary improve on its league-worst average of 246.6 passing yards allowed a game?

It would mean Buffalo reducing its average yards allowed (365.2) per game.

On those passes, they gained 165 yards, an average of 7.5 yards a play, allowing them to build drives.

They are also No. 1 in pass defense (143.8 yards allowed per game).

It features the league's best run defense (62.4 yards allowed per game).

The Jets remain at the bottom of the league in run defense (155.1 yards allowed a game), and this remains a trying season for Cottrell.

The Colts rank sixth in run defense but only 20th in pass defense (223.1 yards allowed per game).

The Tar Heels led the nation in scoring defense last year, and were second a fewest yards allowed.

It will match the leading defensive unit in the nation - Michigan averages 206.9 yards allowed - with the second-leading offense.