At the time, neither district had children with Down syndrome in its schools.

Rex did not tour again with Down during their spring 2011 shows.

Many children with Down syndrome graduate from high school and can do paid work, or participate in university education.

Yet with some ups and downs, the hits kept coming.

Here is a great drama of love with its ups and downs.

The conversations have nothing to do with the ups and downs of the financial market next door.

We have the chance to leave behind the postwar period with the ups and downs of the cold war.

"It has continued, with some ups and downs through the present," he said.

I used to work with kids with downs and they had great lives.

Raising a child with Down syndrome has both challenges and rewards.