And initial data from small or uncontrolled studies were encouraging.

In addition, uncontrolled studies have been performed, one of which reported 72% to 87% rates of successful insertion.

In two uncontrolled clinical studies, about half of participants achieved a complete response after BL22 treatment.

However, this was reported in uncontrolled studies using doses averaging 0.5 mg per day.

It is difficult to determine the contribution of intermittent therapy to the high response rate obtained in this uncontrolled study.

However, this rests solely on two short, uncontrolled studies.

They were uncontrolled studies and had lumped together several different populations.

Objective responses and improved outcomes compared to historical data have been reported from small uncontrolled studies.

Oral valganciclovir was beneficial in one small uncontrolled study (615).

Also, higher doses seem to have some effect in uncontrolled and unpublished studies.