The scheme offers the company the chance of a four-fold rise in audiences for a two-fold increase in money.

One study found that older workers who lost their jobs had a two-fold increase in the risk for subsequent heart attack and stroke.

Tobacco use during pregnancy causes a two-fold increase in the risk of spontaneous abortion.

A micronised formulation of halofantrine with a two-fold increase in absorption was used.

Phosphorylation at Ser19 causes a two-fold increase of activity, through a mechanism that requires the 14-3-3 proteins.

Those who take the gout medicine allopurinol face more than a two-fold increase in risk, and smokers have a 60 percent increase.

These new structures serve the 1.4 million children who are now attending primary school, which is a two-fold increase from five years ago.

Individuals over 40 who played over two hours, had a two-fold increase in chance of injury.

Pregnancy interval makes a difference as women with a 6 months span or less between pregnancies have a two-fold increase in preterm birth.

Citizens will be confronted with a two-fold increase in energy prices.