Kiessling is noted for her discovery of reverse transcriptase activity in normal human cells (Kiessling & Goulian).

Finally, residues 472(G) and 474(D) in the conserved Z motif in ORF2 are required for reverse transcriptase activity [ 46].

The nucleocapsid encloses the viral DNA and a DNA polymerase that has reverse transcriptase activity.

It has reverse transcriptase activity in the presence of Mn ions, allowing PCR amplification from RNA targets.

Tests confirmed the presence of reverse transcriptase activity in crude lysates of retron-containing strains.

Extensive controls lead us to believe that the RNAseH active site is most probably "substrate committed" in a manner similar to the "template commitment" of the reverse transcriptase activity.

The enzyme possesses efficient reverse transcriptase activity in the presence of manganese.

The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component that serves as a template for the telomere repeat.

Reverse transcriptase activity outside of retroviruses has been found in almost all eukaryotes, enabling the generation and insertion of new copies of retrotransposons into the host genome.

The long mRNA is then transported back to the cytoplasm where the virion P protein synthesizes DNA via its reverse transcriptase activity.