I walked out of the building in total despair.

Only those visits had kept her from total despair when the program produced no results.

The scene they had found was one of total despair.

Finally, with a small smile of total despair, she broke the connection.

We called your office in total despair and very concerned of possibly having to close our business.

For the first time, she felt total despair weld her to the spot.

The kiss deepened, driving her hard down into total despair.

Only total despair could have produced the tone that Eleanor had heard.

Yet to find refuge in such fantasy could only be a sign of his total despair.

Some people would react with total despair, expecting the strangers to act like men.