While some patients have fever and other systemic symptoms, many do not.

These systemic symptoms occur especially in people who have severe disease.

This should be considered if patients develop any systemic symptoms .

In some rare instances, more general systemic symptoms such as nausea can be felt.

Systemic symptoms may include fever, night sweats, or weight loss.

Systemic symptoms occur, in general, one to four hours after being bitten by this snake.

In humans, bites from this species can produce severe local and systemic symptoms.

Three patients developed necrosis, and 14 individuals with systemic symptoms had no local swelling at all.

These systemic symptoms suggest that the immune system is involved in Crohn's disease.

Systemic symptoms, which often include heart palpitations, may occur suddenly and relatively soon after the bite.