These numbers represented a substantial decrease from the 1990 level.

"There should be some substantial decrease in medical malpractice rates," he said.

There has also been a substantial decrease in alcohol abuse by drivers.

This substantial decrease had still not reduced crime to levels before the 2001 riots.

A substantial decrease in the population has occurred since the population count of 1940, which was 7,998.

At the same time there was a substantial decrease in the level of cyclin D1.

"What we were seeing was a substantial decrease in the number of drug-related murders."

This can cause a substantial decrease in battery life.

It holds just over 9,000, after substantial decreases for crowd safety.

That would mean a substantial decrease for the old EU-15.