One of the two strands of each fragment, known as the 'guide strand', is then incorporated into the RNA-induced silencing complex (RISC).

This product is then processed by dicer and loaded into the RNA-induced silencing complex (RISC).

Primary siRNA binding to RDE-1 then promotes the formation of the RNA-induced silencing complex (RISC).

The extent to which the miRNA-induced silencing complex (miRISC) is involved in this regulation has not been fully deterined.

The passenger strand is degraded, and the guide strand is incorporated into the RNA-induced silencing complex (RISC).

The mature miRNA is part of an active RNA-induced silencing complex (RISC) containing Dicer and many associated proteins.

The newly synthesized siRNA assemble into endoribonuclease-containing complexes known as RNA-induced silencing complexes (RISCs), unwinding in the process.

Chromodomain-containing proteins also bind methylated histones and appear in the RNA-induced transcriptional silencing complex.

The guide strand of the miRNA is then loaded into RNA-induced silencing complex (RISC) and is then able to pair with its target.

Argonautes, the most well-studied family of nucleic-acid binding proteins, are RNase H-like enzymes that carry out the catalytic functions of the RNA-induced silencing complex (RISC).