The house was significantly modified prior to the 1900s, with the addition of a summer kitchen and second floor.

"He felt the house had been significantly modified and that it was in poor condition."

This development has significantly modified the original natural river network.

These rules only cover tissue which has not been significantly modified.

These two basic legal texts have not been significantly modified for 30 years.

The river has been modified significantly to power water mills over the centuries.

In that case, building designs were significantly modified to meet the financial needs of developers.

Wilderness is generally defined as areas that have not been significantly modified by human activity.

Wilderness is generally defined as a natural environment on Earth that has not been significantly modified by human activity.

Some law schools have significantly modified the traditional curriculum.