Indeed, the Teleport deal was only the most significant instance of a much broader pattern.

Many observers believe there were significant instances of fraud.

It was a significant instance of opposition to the events of the Holocaust.

The most significant instance that McEwen exercised this came when Holt disappeared in December 1967.

The first significant instance occurred in Missouri.

The first significant instance of such interaction took place in November 1919.

When asked to describe the most significant instance of harassment, 75 percent of the women said the incident involved men acting alone.

A significant instance of political blogs influencing politics occurred during the 2006 Virginia Senate campaign.

Our teachers try to be aware of what the children are saying and doing and to record significant instances which tell how thinking is developing.

Despite widespread judicial merger, the distinction between equitable and legal remedies remains relevant in a number of significant instances.