So there are serious questions and significant doubts raised.

But no inmates have come forward to cast significant doubt on the suicide ruling.

Recent research, however, has cast significant doubt on this story, and suggested it was invented by a Canadian journalist during the 1930s.

Does that not cast significant doubt on the other incidents?

Despite the military cautions now being expressed, there is still no significant doubt that the allies can win the war.

More than half say yes; 7 percent have significant doubts.

But they have significant doubts about our ability to lead the country, and we haven't, Bill Clinton hasn't, made the case yet.

Some significant doubts exist about the true identity of Burns first romantic love.

Sport is without doubt socially significant and an important thing for millions of Europeans.

Lack of confirming evidence has cast significant doubt on its origins.