These changes in membrane proteins and fats can result in water loss and increased hemoglobin concentration, which helps transform the cell into rigid sickle shapes.

When the oxygen concentration in the blood is reduced, the red blood cell assumes the characteristic sickle shape.

Their dorsal fin and anal fins are elongated, and their outer edges have a definite sickle shape.

Wednesday looked again and saw only the odd sickle shape of the partially opened horn-rim barrette; tight and hard against the worn denim, it dug into Melony's thigh.

When low on oxygen, this flawed hemoglobin causes blood cells to stiffen and contort into jagged sickle shapes.

She was born with sickle cell disease, a genetic disorder with unpredictable complications that causes the red blood cells to assume an abnormal sickle shape, making it difficult for blood to flow through vessels and deliver oxygen throughout the body.

This tree also has some of the longest leaves of this genus, up to 35 cm with a slight sickle shape.

The ridge has a distinctive sickle shape.

The tail should be expressive, held low when the dog is relaxed, and curved upward in a "sickle" shape when excited or interested in something.

Dragosani leapt on to Borowitz where he fought to struggle to his feet, bore him down again, raised high the sickle shape of silver in his clenched fist.