These data indicate that using a fold-difference of greater than 2 from triplicate samples to select regulated genes will include many false positives.

One could also select genes based on a coefficient of variation filter.

We have confirmed this prediction by randomly selecting bacterial genes in GenBank [ 17 ] , release 130.

Mir et al., 2005 identified FoxI1e (Xema) by selecting genes that were down-regulated under mesoderm-inducing signals in the ectoderm compared to vegetal region of an early blastula embryo.

The I/NI call offers a solution to the main problem of high dimensionality when analyzing microarray data by selecting genes which are measured with high quality.

Absence/presence calls were not considered a priori in selecting significantly regulated genes, but were a post-selection criterion.

The strategy is to select blight-resistance genes during the back crossing, while preserving the more wild-type traits of American Chestnut as the dominant phenotype.

To select genes that were significantly changed in CC (nine samples) verses normal kidney (eight samples) a non-parametric Wilcoxon test was used to calculate a p-value for each gene.

Therefore, selecting differentially regulated genes based only on a single fold change across the entire range of experimental data preferentially selects lowly expressed genes [ 8 ] .

This indicates that a 5% LFC model is confidently selecting differentially regulated genes across the full range of absolute expression.