The maintenance of an ionic pore, as well as a conserved cGMP-binding domain in the AQP1 carboxy tail for regulating activation [ 11 ] , suggests that the ion channel function is likely to be essential for physiological regulatory processes that have yet to be fully appreciated.

The characterization of potentially altered interactions between hypophosphorylated RARα and its cofactors will provide unique insight into how post-translational modification of nuclear hormone receptors regulates repressor release, coactivator recruitment, histone acetylation, and transcriptional activation.

Her research, according to her biography at Harvard, "uses biochemical and genetic approaches to elucidate the molecular pathways that regulate CD4 T helper cell development and activation.

The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade.

Effects of endotoxin on biochemical activity of adherent vascular lung neutrophils We next examined biochemical signaling pathways known to regulate cell survival and activation to determine if their expression was altered in adherent vascular lung neutrophils during acute endotoxemia.

Studies that tested bilinguals with homographs showed that conflicts between target and non-target language readings of the homographs still led to a difference in activation between it and a control, implying that bilinguals are not able to regulate activation in the word identification system.

It regulates eosinophil growth and activation, and thus plays an important role in diseases associated with increased levels of eosinophils, including asthma.

This leads to phosphorylation of the three ITIMs in CD22's cytoplasmic tail, leading to the recruitment of SHP-1 which negatively regulates BCR-based cellular activation.

Recent studies [...] have shown that the estrogen receptor alpha (ERalpha) can be hyperacetylated in response to histone deacetylase inhibition, suppressing ligand sensitivity and regulating transcriptional activation by histone deacetylase inhibitors.