To use TaxPlot, one selects a reference genome and two species for comparison.

These 35 bp reads are compared, using bioinformatics, to a reference genome and assigned to a genetic locus (Figure 7).

Sequence reads are mapped to the reference genome and computational processing of data is carried out.

In addition, it provided updated gene co-ordinates for the most recent human reference genome builds.

With cancer genomes, this usually done by aligning the reads to the human reference genome.

The sequence is then compared to a reference genome and any differences are noted.

By using the variant call format only the variations need to be stored along with a reference genome.

It is the combined "reference genome" of a small number of anonymous donors.

The recommended approach is that of aligning the millions of reads to a "reference genome".

The idea follows from the process of aligning the short transcriptomic reads to a reference genome.