Doesn't he ever doubt himself, or his ability to make a real dent in the disease?

If they could turn him into an informant she knew they'd find out enough to make a real dent in the guild.

"We are making a real dent in our supply of smart munitions."

What sort of policies might make a real dent in unemployment?

Something that can put a real dent in international terrorism?

The Senate would shift 60 percent of spending to drug education and treatment that could put a real dent in demand.

"We're not making any real dent in the need," he said.

Even if it hasn't, enough additional Q-ships will be available to make a real dent in our problems there.

To make a real dent in disease, disability and premature death, people need to accept the whole package, not just one small part.

More are on their way, although it will take years if not decades to make a real dent in the problem.