The disease is uncommon in people younger than 65 and is rare before the age of 45.

MS cases are rare before puberty, but they can happen.

Accounts of a schizophrenia-like syndrome are rare before the 19th century.

The disease is very rare before the age of 40.

Metal screws used as fasteners were rare in Europe before the 15th century, if known at all.

Children over the age of five can develop schizophrenia, but it is very rare before adolescence.

There is also the general observation that democracy was very rare before the industrial revolution.

Although the disease is rare before age 50, experts believe that most elderly men have at least traces of it.

It is most common in boys past puberty, and rare before the age of 10.

Conversation was rare during the slow walk before dawn.