"This treatment has been proven safe and effective by multiple clinical studies," she said.

In those cases, the Government has decided that treatments must be proven safe and effective before they are offered on a large scale.

So far, this type of therapy has proven both safe and beneficial.

The Swallow, which proved robust and safe, was popular in service.

The products have not been proven safe and effective for their intended use.

It wasn't his business to question this curious process so long as the road proved safe.

Doctors said that if the surgery proves safe and effective, demand from patients will be heavy.

Those who market the program insist that it has been proven safe and effective.

If a human form of the vaccine can be developed and proved safe, further studies should answer these questions.

"Many things have yet to be proven safe and effective."