Whether membership marks a more profound transformation is another question.

A far more profound transformation followed with the arrival of the railways, beginning in the late 1830s.

A profound transformation took place, one which was far from obvious to the casual outside observer.

Around age 3 to 4, children's understanding of mental life undergoes a profound transformation.

Seldom has a region of America undergone a more profound economic transformation than these three states.

From that moment a profound transformation had begun in Adrian.

You don't have to rely on drugs to see profound transformation.

It makes little sense to blame one company for the pain caused by a profound economic transformation.

The mid-19th century was a time of profound transformation in French government and society.

For all its importance to the country's economy, the $10 billion Swiss watch industry is going through a profound transformation.