This contrast reflects, among other things, a profound national shift in political power over the last three decades.

Rejection, they said, would signal a profound shift in attitudes toward public spending for environmental programs.

But something happened and there was a profound shift in the mood of the country.

"We're dealing with a profound historical shift in the economy that has been enabled by technology."

He has been helped by the profound shift in government to a more conservative outlook over the last decade.

This marks a profound shift in emphasis for planning policy.

Current and former Amnesty officials say the report illustrates a profound shift at the world's best known rights organization.

Even before the scandal, the financial industry was undergoing slow but profound shifts.

The general's caution reflects what appears to have been a profound shift in his position.

Is it also leading to a profound shift in attitudes to women?