Her blasphemy had touched his most profound doubts.

There remain within me, however, profound doubts that every use of melange always brings virtue.

Did he ever have a moment of profound doubt, when he thought that the city could not come back and his every effort was wasted?

But certain other bits he uttered stirred the beginnings of a profound doubt in her.

There was profound doubt in his voice.

Isn't it the moment of most profound doubt that gives birth to new certainties?

He has indeed the most profound doubts as to whether St Matthew wrote his own gospel.

And many education experts harbor profound doubts that choice makes sense as a major strategy for overhauling schools.

Quintilius Rousse glanced at me sidelong, profound doubt in his blue gaze.

Celan's profound spiritual doubt contrasts with U2 members' previous religious certainties.