In smooth muscle of blood vessels the principal effect is vasoconstriction.

Their principal acute effect in humans is a skin rash called chloracne.

For atoms in the gas phase the principal effects are Doppler and pressure broadening.

The principal effect of this temper was visible in his features and tones.

The principal effect of the category changes will be an improvement in the ratings of many international stock funds.

Its principal effects are increased production and release of corticosteroids.

The principal effects of these products are vasodilation and smooth-muscle contraction.

The principal effect would be due to their interaction with the heavy positively-charged matter in the atoms.

But the principal effect, they say, may have been to give Russia's civil liberties and military policies an even more conservative cast.

The principal effect of immigration is on population effective without substantially modifying the structure.