This question presents a novel and perplexing issue of constitutional law.

But there is a deeper, more perplexing issue.

Drug abuse, child molestation and AIDS are among the perplexing issues parents sometimes feel compelled to explain, even to preschool children.

"The Beardstown Ladies" presents a perplexing issue to judges in California and New York.

Then there is the perplexing issue of the mind-set at NASA.

For the next two decades the Goshute people had to struggle with a number of important and perplexing issues.

Dramatic efforts have ever since been made to remove this long perplexing issue.

One potentially perplexing issue in a co-op's annual election, Ms. Falik said, is proxy voting.

"I'm looking forward to studying the committee's report and working with them to ensure adequate research funding to find answers to these perplexing medical issues," he said.

These artists, like others using biotechnology, employ serious science in their projects, but they also poke serious fun at some of society's most perplexing issues.