To begin with, this was the only such pattern in existence, but then a new mutation arose.

Alternatively, the mutations may have arisen shortly after the exodus from Africa.

Without these genes mutations in the urogenital system arise.

Uncontrolled ecosystems were precisely those in which unexpected mutations and disease organisms arose.

Moreover, it is also known that many genetic variations are associated with the geographical and historical populations in which the mutations first arose.

They should have ceased to exist when a superior mutation arose.

On the other hand, should an advantageous mutation arise, it is likely to show its effect sooner and more thoroughly.

The mutations probably arose as people encountered toxins, radioactivity and other carcinogens in the environment.

De novo diseases occur when a new mutation arises in the person that was not inherited through either parent.

Yet it somehow managed to make do and pass on the trait until the next mutation arose.