These methodological difficulties are associated with a more general problem of deriving generalizations from corpuses.

Man-made threats such as nuclear war or nanotechnology are even harder to predict, due to the inherent methodological difficulties in the social sciences.

One of the letters seems to support our conclusion, whereas the two others focus on possible methodological difficulties.

In any case, methodological difficulties should not dictate epistemology.

Researchers cautioned that such genetic signature studies were fraught with methodological difficulties.

The important point is to recognize that these methodological difficulties exist and allow awareness of them to influence our interpretation of experimental results.

There were considerable methodological difficulties, not all of which were overcome.

There are particular methodological difficulties, beyond the level of relative formality or informality.

They are not yet included in the conclusions because there are some methodological difficulties.

Although some research has been done on the correlation between climate and conflict, methodological difficulties and inconclusive results have caused lots of confusion.