It's a master regulator that can send a very loud signal at critical points throughout development.

But the cell must be ready at any moment to activate one specific master regulator as soon as its fate is determined.

They found it had sought out some 200 sites where many of the master regulator genes of human cells are located.

Finally, a few master regulators sit on top of the hierarchy and only regulate other genes.

Even the master regulators wouldn't get produced if there weren't some basic machinery around to transcribe genes.

Finally, the master regulators are called by no one, although they require calls to other functions to get their work done.

KLF14 appears to be a master regulator of gene expression in adipose tissue.

AP-2 alpha also functions as a master regulator of multiple transcription factors in the mouse liver.

PGC-1α, in particular, is thought to be a master regulator.

Hepcidin is thus the "master regulator" of human iron metabolism.