These offer an opportunity to give a present which makes a real difference to the lives of children.

The voice on the other end of the phone has made all the difference to his life.

Whatever words you use, the change it will make to your life is the same.

They don't let the new job make any great difference to their lives.

This is a particularly good time to consider making major changes either to your job, home or personal life.

Does that really make such a difference to your life?

It's going to make a big difference to my life.

How much difference does this really make to people's lives?

They see it as making a difference to people's lives.

We've reached a place where we can leave all that behind, make a new start to our lives.