The term is less common in modern texts, and was originally derived from a dichotomy with major tranquilizers, also known as neuroleptics or antipsychotics.

In the meantime I'd recommend a short course of a major tranquilizer.

Because amoxapine has some effects that are similar to those of major tranquilizers, it may work better in patients who have agitation or anxiety along with depression.

Later came the wide spread adoption of major tranquilizers such as chlorpromazine and the drug reserpine.

The drug, a phenothiazine, a class of major tranquilizers, also dries upper airways.

Since anxiolytics such as benzodiazepines and major tranquilizers add to sedation, they should only be used to address anxiety, depression, disturbed sleep or muscle spasm.

However, since major tranquilizers are powerful medications that can produce serious and sometimes permanent side effects, they should be prescribed and used with extreme caution.

In the late 1950s the most widely used term was "neuroleptic", followed by "major tranquilizer" and then "ataraxic".

"Low potassium and major tranquilizers don't mix," he told her.

In the fifties, when the major tranquilizers came in, I taught a lot.