According to the Köppen system, Chile within its borders hosts at least seven major climatic subtypes.

But they inherit it in one of six combinations of three major genetic subtypes.

ERMS is the more common of two major subtypes of rhabdomyosarcoma, the other being alveolar rhabdomyosarcoma.

There are three major subtypes of vein style uranium mineralisation:

Class B foams have two major subtypes.

The o'nyong-nyong virus (ONNV) has at least three major subtypes, or strains, the genomic sequences of which are currently available on genome databases.

There are two major subtypes of T cells: the killer T cell and the helper T cell.

Adenocarcinomas are highly heterogeneous tumors, and several major histological subtypes are currently recognized:

Earlier publications categorized neuroblastomas into three major subtypes based on cytogenetic profiles:

There are four major subtypes of opioid receptors: