Research into the history of corporate finance during the period before 1914 has been limited by two major difficulties.

The major difficulty in the use of natural gas is transportation.

The sheer size of the buildings being a major difficulty.

It clearly takes us some way, but there are still major difficulties.

From 2001 to 2003 they sponsored the club after it had got into major financial difficulties.

This situation is leading to major difficulties in the economy and putting jobs at risk.

Despite the major difficulties during the preparations, this meeting can be considered a success.

I do not think this presents major difficulties at all.

There are also a few other major practical difficulties, such as social security problems, particularly in the field of health care.

"Unfortunately, that is a major difficulty in any study like this," he said.