Next week's Senate vote could have major consequences on the treaty's future.

Whether they talked I don't think is of major consequence.

It's a highly technical decision that will have major political consequences.

While the outcome of the game will have major consequences, it might not be the teams' only meeting this season.

In Washington, the deal is likely to have other major consequences for the telecommunications industry.

There is no question that the decision has major consequences.

"I do not believe this will have major consequences," he said.

Otherwise, there may be major consequences in terms of health.

We are only talking about a small group, but what they do can have major consequences.