Over six and a half years, Schering filed 37 major amendments to its application.

During his period in office the Government carried out seven major amendments to the 1973 Constitution.

All the major amendments of the trade bill have been considered.

It took force in 1995 and underwent a major amendment in 2009.

It has substantially survived for over 150 years in several jurisdictions without major amendments.

The first major amendments to the food and drug safety laws since 1938 were carried out.

The current cohesion policy requires improvements, without any major amendments.

However, there were some major amendments on which we also achieved a broad consensus.

With the common position, we are today debating the first major amendment to this directive.

One major amendment to the first half still remains for consideration.