The problem is especially severe in developing countries, which are least able to provide the long-term intensive treatment that asthma requires.

But the greatest need, I thought, was to help low-wage workers who are least able to protect themselves.

They often deliver the most expensive care to the people who are least able to pay.

Social workers would say that the economy is placing more pressure on families who are least able to cope.

It's exploiting those who are least able to handle it.

These individuals are least able to secure normal, lower-interest-rate forms of credit.

Because it is they, the poor, who are least able to deal with the new generation of resistant pathogens.

Thus some people tend to have to pay more for their health insurance when they are sick and/or are least able to afford it.

Who would be least able to bear it?

The developing countries are suffering particularly badly from the effects of the crisis, and they are least able to do anything about it.