The global financial crisis has had a large impact on America.

It is well known that changes in energy costs have a large impact on economic growth rates.

We think that big data is going to have a large impact on 2012.

"It's one that has a large impact on the way we run our schools."

A relatively small change in the interest rate can have a large impact.

Mining has had a large impact on the growth of the area.

The series made a large cultural impact, which continues today.

D&D also had a large impact on modern video games.

The plan could have a larger impact than his cuts.

Environmental conditions can have a large impact on this plant.