The political landscape had changed irreversibly in the aftermath of the war.

Realizing that the political situation had changed irreversibly, however, he decided to turn himself in to the military authorities.

At some high temperature stage the chemical identity of the matter is irreversibly changed: when you cool down.

Has this relationship changed irreversibly for the better since the exposure of the hacking scandal?

Within a span of twenty years, Ute life had been irreversibly changed.

The last quarter-century has irreversibly changed the way we perceive and act towards each other.

Some properties may change irreversibly by a few per cent from soldering.

Contemporary accounts shed light on how medieval Britain was irreversibly changed.

They are being changed irreversibly and we do not know where we are going.

This work substantially and irreversibly changed the canal network.