Our deepest sympathy to his family and colleagues on their irreplaceable loss.

Faced with the final choice, the irreplaceable loss, that may be what many patients and families need.

But as the long night drew to a close, he felt only one thing: a sense of irreplaceable loss.

That same year the large studio burned, with the irreplaceable loss of the sculptor's correspondence, his sketch books, and many works in progress.

It was a tragic and irreplaceable loss, but none of the greens survived to pursue the attack.

If not, she would not be an irreplaceable loss.

A leaking roof was to cause irreplaceable losses of the initial tablets.

What were her immature fears compared with his irreplaceable loss?

That to me is an irreplaceable loss.

Nature has wrought enormous and irreplaceable losses, especially in terms of human life and property.