The primary goal of therapeutic footwear is to prevent complications, which can include strain, ulcers, calluses, or even amputations for patients with diabetes and poor circulation.

Possible side effects include stomach irritation, ulcers, mental irritation and long-term effects (weakening bones and muscles).

Usually, prevalent symptoms include canker sores or ulcers in the mouth and on the genitals, and inflammation in parts of the eye.

These include liver problems, gout, ulcers of the digestive tract, loss of vision, high blood sugar, irregular heartbeat, and other serious problems.

Causes of oropharyngeal lesions include oral cancer, ulcers, and infections such as Ebola.

Other causes include: gastric or duodenal ulcers, Mallory-Weiss tears, cancer, and angiodysplasia.

These include blindness, amputation, vascular ulcers, stroke, kidney failure and heart disease.

But the hazards include mood swings, ulcers and stomach inflammation.

Complications may include necrosis and ulcers of the rectal tissue.

Pet owners were more likely to suffer from illnesses that included high blood pressure, high cholesterol, ulcers, depression and kidney disease.