The only important drawback to the pleasure of elk-hunting is the constant loss of the dogs.

The most important drawback in case-control studies relates to the difficulty of obtaining reliable information about an individual's exposure status over time.

But these systems also have important drawbacks.

Remarkably not included among the perceived imperfections was the one-man turret, though it is today typically mentioned as its single most important drawback.

However, it also has important drawbacks.

Unfortunately, it suffers from an important drawback.

The most important drawback, though, is the limited selection of flights offered to and from the alternative airports.

Adverse Effects But the antidepressants had important drawbacks.

"Since I recovered my health here, I've tried to figure a way around the most important drawback that all singers face."

Its only important drawbacks are that it is flammable and a greenhouse contributor.