However, "we met with a great misfortune in the loss of our cow."

She loved children very much, and it was our great misfortune that we never had any.

No, look you here, their republic would be a great misfortune for everybody!

But I feel as if some great misfortune were hanging over us.

A year or two later a great misfortune happened to him.

But great misfortune was the story of the season as six key players suffered long term injuries all in September.

She suffered great misfortune at an early age with the death of her father.

It was my great misfortune to arrive after his death.

It is believed that in these years the person may meet with great misfortune.

It's a great misfortune that most of those who returned right after the Extinction didn't have the means to study what they saw.