Even a few degrees' rise in average global temperature could have extreme regional consequences.

A delay in care or glitch connected to boarding can have extreme consequences for patients.

This may be the extreme consequence of a health service which, although it insists that it puts patients first, often doesn't do so at all.

Russia's political leaders have not helped by warning of civil war and other extreme consequences if next month's presidential elections leave the country divided.

Even that was not the most extreme consequence of the bad weather.

He threatened extreme consequences if the order is not obeyed.

Their actions sometimes have extreme consequences, but often for others, for which they themselves show no remorse whatsoever.

These experiences have extreme consequences and an interpretation of them will occupy the next three chapters.

The way of infiltration is one-way only and any attempt to block the process ends in extreme consequences.

These delusions carry with them extreme consequences in the real world.