This is significant especially where the original data was produced on technology at a lower level than currently possible.

Jerusalem, as the site of the Temple, is considered especially significant.

This is especially significant when you consider how dark a block of text looks.

It would have been especially significant in increasing the number of children who got help.

He said that one line of dialogue in the film was especially significant.

Especially significant is the fact that it was the military who removed him.

That last point is especially significant to me as a mother.

May I return to two of them, which seem to be especially significant.

Which aspects have been especially significant to us as a Parliament?

This is not an especially significant increase from the 1881 census at which time 178 people were living there.