By the beginning of 1947 the drug began to be available commercially.

But within five to 10 years, the drug usually begins to lose its effectiveness.

The drug that kept the pain at bay began to make his voice thick.

Serve a large dinner in the evening, when the drug is beginning to wear off.

The drugs began to kick in, and his reflection looked a little better.

By the time Lotta had finished, the new drug was beginning to act.

Should the tests be used only when drugs begin to fail?

Almost all Americans who use drugs begin before they are 21.

As the drugs began to take effect, though, he was filled with a sudden panic.

Herewiss sat there and felt the drug begin to work.