I didn't need medical training to see that there was something dreadfully wrong with the old man.

Something was dreadfully wrong, and he could not understand what.

Instead, he agreed with her that something must be dreadfully wrong.

If something goes dreadfully wrong with the building, they have to pay for it.

There was something dreadfully wrong with the way he moved.

This is dreadfully wrong advice and I hope you will not act upon it.

He couldn't move, and began to think something had gone dreadfully wrong.

When he didn't call one evening I knew immediately that something was dreadfully wrong.

Then, as was usual for this day, everything went dreadfully wrong.

But even as the words came out I knew something was dreadfully wrong.