Experience with the new AIDS drugs may foreshadow the difficult trade-offs that await taxpayers and policy makers as scientists develop costly treatments for other diseases like cancer or Alzheimer's.

Adding to Welfare's Despair As a mother on welfare in California, Sonja Blutgarten makes difficult trade-offs every day.

Indeed, this crisis provides an opportunity to make some difficult trade-offs in favour of growth that might get parked in the "too difficult" box in calmer times.

And the dispute illustrates the kind of difficult trade-off that will increasingly be encountered as the global drive to protect the environment runs into economic and practical obstacles.

The rating of the ESM was also in doubt, as it would "face a difficult trade-off between higher lending volume and achieving a AAA rating".

The officials said the board would be presented with three choices, each of them involving difficult trade-offs for riders.

Seeking Tough Trade-offs "We're going to force the Administration into making very difficult trade-offs," Senator Kasten said today.

A decision to file for bankruptcy requires a difficult trade-off: a company gains time, but loses autonomy.

Standard electric motors pose a difficult trade-off for engineers.

It's a difficult trade-off if you want to have fresh produce in the off-season.