Many constructs are awkward or impossible to express using macros, or use a significantly different syntax.

Each requires virtuosity, but with a different syntax.

Different service providers use different syntax for this.

Powershell is way nicer than Bash, it just has a different syntax.

Many data sources share the same semantics but have different syntax, or format to describe the same concepts.

One way to handle this difficulty is to choose a different syntax.

Sometimes different programs use different syntax in the same operating system.

Imperative sentences sometimes use different syntax than declarative or other types of clauses.

That's to be expected: Otherwise, they wouldn't really be different languages, just a different syntax and minor variations on a single language theme.

Or perhaps the different syntax of the languages?