In mid-2007, structural defects arose around the sports complex, resulting in a possibility of relocating the whole facility.

Classically the defect arises in two ways:

The defect in the immunoglobulins presumably arises during somatic hypermutation.

Cardiomyocytes are the basis for the correct architectural scheme of the heart, and if defects arise in these structures, proper heart development is likely unattainable.

The difficulty, of course, is demonstrating that the defects arose from the doctor's negligence.

The final structure is a mixture of ordered regions, where the local order is similar to that of the template, and defects arising from the embedding.

That's how the defect arose.

Where the defect arises from a production defect which renders the product unsafe, then liability will attach under the Act.

Even if they pass that test they still have to pass the second hurdle of being "in consumer use" when the defect arises.

The defect arises because the cell's machinery for handling chromosome recombination gets overloaded when it has to deal with repeated copies of the same gene.