It turned out that the Baylor team had inadvertently created mice that possessed unusually large amounts of p53 in their cells.

The general methods for creating chimeric mice can be summarized either by injection or aggregation of embryonic cells from different origins.

That chromosome, developed by Kirin, has been used to create mice that make human antibodies.

Recently, researchers have been able to create transgenic mice with most of human chromosome 21 (in addition to their normal chromosomes).

Recombinant antibody engineering involves the use of viruses or yeast to create antibodies, rather than mice.

Jaenisch has focused on creating transgenic mice to study cancer and neurological diseases.

The team announced recently that it had created mice that generated substantial amounts of the protein attached to fat globules in their milk.

However, in 1989, the ability to create mice with custom "knockout" genomes changed the game.

Dr. Sanes and his colleagues wanted to go beyond the test tube, so they created mice that lacked agrin.

Charles River Laboratories, which creates genetically altered mice and rats, was one of the biggest holdings in the biotech fund last quarter.